The DNA in the organisms will replicate when it goes through cell mitosis in eukaryotes. The replication will occur as the cell grows and will occur countless of times in the whole period of the organism.
Act I: Initiation
In a specific point in the DNA, there's a orihin of replication, which is possible to have multiple of them. An rnzyme called helicase will come in and start to unwind the DNA. The helicase will break the hydrogen bonds between the base pairs. The new single strand will be stabilized by the enzyme called single-strand-binding protein. When the DAN start to unwind, it will create two Y- shape areas at each ends called replication fork,results in a replication bubble.
Act II: Elongation
When elongation starts DNA polymerase II will attatch to a new RNA nucleotides to the parental strand in the 5' to 3' direction.
When the DNA replicates, the strand unwinds, creating two tamplates. The two templates all have different names. One of them is called the Leading strand, and the other one is called lagging strand. DNA polymerase will move in the same direction as the replication fork on the leading strand, attatching the nucleotides to the leading strand. On the lagging strand, DNA polymerase will have to move in the opposite direction , and the new strand will occur in forms of short segments called Okazaki fragments.
RNA prime is a short fragement of RNA produced by Primase. Once a prime is in place, a new DNA fragment is generated, which is the Okazaki fragment.
Eventually, the DNA polymerase I will remove the RNA pimer, and then the DNA ligase will join all the discontinous Okazaki fragments together.
Act III: Termination
As soon as the new strand is finished, it will rewind automatically with the parental strand. The two new DNA molecules separate from each other ans the replication machine is stopped.
Act II: Elongation
When elongation starts DNA polymerase II will attatch to a new RNA nucleotides to the parental strand in the 5' to 3' direction.
When the DNA replicates, the strand unwinds, creating two tamplates. The two templates all have different names. One of them is called the Leading strand, and the other one is called lagging strand. DNA polymerase will move in the same direction as the replication fork on the leading strand, attatching the nucleotides to the leading strand. On the lagging strand, DNA polymerase will have to move in the opposite direction , and the new strand will occur in forms of short segments called Okazaki fragments.
RNA prime is a short fragement of RNA produced by Primase. Once a prime is in place, a new DNA fragment is generated, which is the Okazaki fragment.
Eventually, the DNA polymerase I will remove the RNA pimer, and then the DNA ligase will join all the discontinous Okazaki fragments together.
Act III: Termination
As soon as the new strand is finished, it will rewind automatically with the parental strand. The two new DNA molecules separate from each other ans the replication machine is stopped.
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